Article
Association between prevalence of chloroquine resistance and unusual mutation in pfmdr-I and pfcrt genes in India.
The American journal of tropical medicine and hygiene - 1 May 2013
Das Sabyasachi, Chakraborty Subhankari Prasad, Hati Amiya Kumar, Roy Somenath
Abstract excerpt
This study deals with the underlying causes of failure of chloroquine in the treatment of Plasmodium falciparum infection in some malaria-endemic regions of India. Samples were collected from 141 patients in Purulia from March of 2007 to April of 2008. In vitro drug susceptibility tests, parasitic DNA isolation followed by polymerase chain reaction, and restriction fragment-length polymorphisms of different...
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