Association between prevalence of chloroquine resistance and unusual mutation in pfmdr-I and pfcrt genes in India.

doi:10.4269/ajtmh.11-0795

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Article

Association between prevalence of chloroquine resistance and unusual mutation in pfmdr-I and pfcrt genes in India.

The American journal of tropical medicine and hygiene - 1 May 2013

Das Sabyasachi, Chakraborty Subhankari Prasad, Hati Amiya Kumar, Roy Somenath

Abstract excerpt

This study deals with the underlying causes of failure of chloroquine in the treatment of Plasmodium falciparum infection in some malaria-endemic regions of India. Samples were collected from 141 patients in Purulia from March of 2007 to April of 2008. In vitro drug susceptibility tests, parasiti...

Topics

Antimalarials
Child
Child, Preschool
Chloroquine
DNA, Protozoan
Drug Resistance
Female
Genotype
Humans
India
Malaria, Falciparum
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Multidrug Resistance-Associated Proteins

Mutation

Parasitic Sensitivity Tests

Plasmodium falciparum

Polymerase Chain Reaction

Polymorphism, Restriction Fragment Length

Source

Open in PubMed Open full text

Identifiers

PMID: 23509121
DOI: 10.4269/ajtmh.11-0795
PMCID: PMC3752744

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-23509121-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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