Article
Phosphoregulation of Twist1 provides a mechanism of cell fate control.
Current medicinal chemistry - 1 Jan 2008
Firulli Anthony B, Conway Simon J
Abstract excerpt
Basic Helix-loop-Helix (bHLH) factors play a significant role in both development and disease. bHLH factors function as protein dimers where two bHLH factors compose an active transcriptional complex. In various species, the bHLH factor Twist has been shown to play critical roles in diverse developmental systems such as mesoderm formation, neurogenesis, myogenesis, and neural crest cell migration and...
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