Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Twist and Notch negatively regulate adult muscle differentiation in Drosophila.

Development (Cambridge, England) - 1 Apr 1998

Anant S, Roy S, VijayRaghavan K

Abstract excerpt

Twist is required in Drosophila embryogenesis for mesodermal specification and cell-fate choice. We have examined the role of Twist and Notch during adult indirect flight muscle development. Reduction in levels of Twist leads to abnormal myogenesis. Notch reduction causes a similar mutant phenotype and reduces Twist levels. Conversely, persistent expression, in myoblasts, of activated Notch causes continued twist...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drosophila Proteins
Share to Cell Differentiation
Share to Drosophila melanogaster

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Developmental

Share to Membrane Proteins

Share to Nuclear Proteins

Share to Phenotype

Share to Transcription Factors

Source

Identifiers

PMID: 9502718
DOI: 10.1242/dev.125.8.1361

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Twist and Notch negatively regulate adult muscle differentiation in Drosophila.PMID 9502718Read ↗

Twist is required for muscle template splitting during adult Drosophila myogenesis.Semantic proximity Read ↗

twist and snail as positive and negative regulators during Drosophila mesoderm development.Semantic proximity Read ↗

Patterns of gene expression during Drosophila mesoderm development.Semantic proximity Read ↗

Twist functions in mouse development.Semantic proximity Read ↗

Twist function is required for the morphogenesis of the cephalic neural tube and the differentiation of the cranial neural crest cells in the mouse embryo.Semantic proximity Read ↗

Discrete levels of Twist activity are required to direct distinct cell functions during gastrulation and somatic myogenesis.Semantic proximity Read ↗

Twist plays an essential role in FGF and SHH signal transduction during mouse limb development.Semantic proximity Read ↗

Twist regulates cytokine gene expression through a negative feedback loop that represses NF-kappaB activity.Semantic proximity Read ↗

A Drosophila model to study the functions of TWIST orthologs in apoptosis and proliferation.Semantic proximity Read ↗

Caenorhabditis elegans twist plays an essential role in non-striated muscle development.Semantic proximity Read ↗

The Drosophila toll gene functions zygotically and is necessary for proper motoneuron and muscle development.Semantic proximity Read ↗

Muscle development is independent of innervation during Drosophila embryogenesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.