Article
Twist and Notch negatively regulate adult muscle differentiation in Drosophila.
Development (Cambridge, England) - 1 Apr 1998
Anant S, Roy S, VijayRaghavan K
Abstract excerpt
Twist is required in Drosophila embryogenesis for mesodermal specification and cell-fate choice. We have examined the role of Twist and Notch during adult indirect flight muscle development. Reduction in levels of Twist leads to abnormal myogenesis. Notch reduction causes a similar mutant phenoty...
Topics
- Animals
- Cell Differentiation
- Drosophila Proteins
- Drosophila melanogaster
- Embryo, Nonmammalian
- Flight, Animal
- Gene Expression Regulation, Developmental
- Membrane Proteins
- Muscles
- Myosins
- Nuclear Proteins
- Phenotype
- Pupa
- Receptors, Cell Surface
- Receptors, Notch
- Transcription Factors
- Twist-Related Protein 1
- Wings, Animal