Article
Differential effect of caffeine intake in subjects with genetic susceptibility to Parkinson's Disease.
Scientific reports - 2 Nov 2015
Kumar Prakash M, Paing Swe Swe Thet, Li HuiHua, Pavanni R, Yuen Y, Zhao Y, Tan Eng King
Abstract excerpt
We examined if caffeine intake has a differential effect in subjects with high and low genetic susceptibility to Parkinson's disease (PD), a common neurodegenerative disorder. A case control study involving 812 subjects consisting of PD and healthy controls were conducted. Caffeine intake assessed by a validated questionnaire and genotyping of PD gene risk variant (LRRK2 R1628P) was carried out. Compared to...
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