Article
Membrane raft association is a determinant of plasma membrane localization.
Proceedings of the National Academy of Sciences of the United States of America - 10 Jun 2014
Diaz-Rohrer Blanca B, Levental Kandice R, Simons Kai, Levental Ilya
Abstract excerpt
The lipid raft hypothesis proposes lateral domains driven by preferential interactions between sterols, sphingolipids, and specific proteins as a central mechanism for the regulation of membrane structure and function; however, experimental limitations in defining raft composition and properties have prevented unequivocal demonstration of their functional relevance. Here, we establish a quantitative, functional...
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