Article
Renin-angiotensin-aldosterone system related gene polymorphisms and urinary total arsenic is related to chronic kidney disease.
Toxicology and applied pharmacology - 1 Sept 2014
Chen Wei-Jen, Huang Ya-Li, Shiue Horng-Sheng, Chen Tzen-Wen, Lin Yuh-Feng, Huang Chao-Yuan, Lin Ying-Chin, Han Bor-Cheng, Hsueh Yu-Mei
Abstract excerpt
A recent study demonstrated that an increased risk of chronic kidney disease (CKD) was associated with high urinary total arsenic levels. However, whether genomic instability is related to CKD remains unclear. An association between CKD and genetic polymorphisms of regulation enzymes of the renin-angiotensin-aldosterone system (RAAS), such as angiotensin-converting enzyme (ACE), angiotensinogen (AGT), angiotensin...
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