Article
Genetic polymorphisms of ORAI1 and chronic kidney disease in Taiwanese population.
BioMed research international - 1 Jan 2014
Hwang Daw-Yang, Chien Shu-Chen, Hsu Yu-Wen, Kao Chih-Chin, Cheng Shih-Ying, Lu Hui-Chen, Wu Mai-Szu, Chang Jer-Ming
Abstract excerpt
Taiwan has very high incidence and prevalence of chronic kidney disease (CKD), which easily progresses to end-stage renal disease (ESRD). The association between inflammation and CKD has been explored in several studies. ORAI1 functions as a pore-forming subunit of the store-operated calcium channels which are involved in the regulation of immune system. Hence, we conducted a case-control study to determine...
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