Article
Analysis of angiotensin II type 1 receptor and osteoprotegerin gene polymorphism on the risk of cardiovascular mortality risk and progressivity of chronic kidney disease.
Minerva medica - 1 Aug 2024
Susilo Hendri, Pikir Budi S, Tjipta Nathanael J, Alsagaff Mochamad Y, Thaha Mochammad, Suryantoro Satriyo D, Wungu Citrawati Dk, Amin Mochamad, Rampengan Derren D, Ramadhan Roy N, Papageorgiou Platon, Gauci Ryan, Tóthová Rebeka
Abstract excerpt
BACKGROUND: Chronic kidney disease (CKD) is a significant global public health issue with increased risk of atherosclerotic cardiovascular disease (ASCVD) and cardiovascular mortality. Single nucleotide polymorphisms (SNPs) on angiotensin II type 1 receptor (AT1R) A1166C and osteoprotegerin (OPG) C950T gene have received significant attention as a genetic risk factor for cardiovascular disease and CKD. METHODS:...
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