Article
Revisiting liver disease progression in HIV/HCV-coinfected patients: the influence of vitamin D, insulin resistance, immune status, IL28B and PNPLA3.
Liver international : official journal of the International Association for the Study of the Liver - 1 Mar 2015
Mandorfer Mattias, Payer Berit A, Schwabl Philipp, Steiner Sebastian, Ferlitsch Arnulf, Aichelburg Maximilian C, Stättermayer Albert F, Ferenci Peter, Obermayer-Pietsch Barbara, Grabmeier-Pfistershammer Katharina, Trauner Michael, Peck-Radosavljevic Markus, Reiberger Thomas
Abstract excerpt
BACKGROUND & AIMS: To perform a comprehensive study on independent modulators of liver fibrosis progression and determinants of portal pressure considering immune status, insulin resistance (IR), serum 25-hydroxyvitamin D (25(OH)D) levels, genetic variants of patatin-like phospholipase domain-containing protein 3 (PNPLA3) and interleukin 28B (IL28B) in a thoroughly documented cohort of HIV/hepatitis C-coinfected...
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