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Single nucleotide polymorphisms in PNPLA3, ADAR-1 and IFIH1 are associated with advanced liver fibrosis in patients co-infected with HIV-1//hepatitis C virus.

AIDS (London, England) - 1 Dec 2021

Franco Sandra, Horneros Judith, Soldevila Laura, Ouchi Dan, Galván-Femenía Iván, de Cid Rafael, Tenesa Montserrat, Bechini Jordi, Perez Ricardo, Llibre Josep M, Clotet Bonaventura, Tural Cristina, Martínez Miguel Angel

Abstract excerpt

OBJECTIVE: Nonalcoholic fatty liver disease (NAFLD), insulin resistance and liver fibrosis are prevalent in individuals co-infected with HIV type 1 (HIV-1)/hepatitis C virus (HCV), even after HCV eradication. Our aim was to evaluate single nucleotide polymorphisms (SNPs) associated with advanced liver fibrosis in HIV-1/HCV co-infected patients. DESIGN/METHODS: In a cohort of 102 participants, we genotyped 16 SNPs...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Interferon-Induced Helicase, IFIH1

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Share to Liver Cirrhosis

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Share to Phospholipases A2, Calcium-Independent

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Identifiers

PMID: 34482352
DOI: 10.1097/QAD.0000000000003066

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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