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Article

Sequence variations of full-length hepatitis B virus genomes in Chinese patients with HBsAg-negative hepatitis B infection.

PloS one - 1 Jan 2014

Huang Fung-Yu, Wong Danny Ka-Ho, Seto Wai-Kay, Zhang An-Ye, Lee Cheuk-Kwong, Lin Che-Kit, Fung James, Lai Ching-Lung, Yuen Man-Fung

Abstract excerpt

BACKGROUND: The underlying mechanism of HBsAg-negative hepatitis B virus (HBV) infection is notoriously difficult to elucidate because of the extremely low DNA levels which define the condition. We used a highly efficient amplification method to overcome this obstacle and achieved our aim which was to identify specific mutations or sequence variations associated with this entity. METHODS: A total of 185 sera and...

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Share to DNA, Viral
Share to Genome, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepatitis B, Chronic

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Source

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Identifiers

PMID: 24901840
DOI: 10.1371/journal.pone.0099028
PMCID: PMC4047052

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