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Article

LRP5 polymorphisms and response to alendronate treatment in Chinese postmenopausal women with osteoporosis.

Pharmacogenomics - 1 Apr 2014

Zhou Pei Ran, Liu Hai Juan, Liao Er Yuan, Zhang Zhen Lin, Chen De Cai, Liu Jian, Wu Wen, Xing Xiao Ping, Xia Wei Bo, Xu Ling, Li Mei

Abstract excerpt

AIM: To investigate the association between LRP5 gene polymorphisms and response to alendronate in Chinese osteoporotic women. MATERIALS & METHODS: Six hundred and thirty nine Chinese postmenopausal women with osteopenia or osteoporosis were included and received alendronate treatment. The A1330V polymorphism of LRP5 was investigated. Bone mineral density (BMD) and bone turnover markers (ALP and β-isomerized...

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Identifiers

PMID: 24897288
DOI: 10.2217/pgs.14.12

Genes

LRP5

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