Article
LRP5 Polymorphisms and response to risedronate treatment in osteoporotic men.
Calcified tissue international - 1 Mar 2009
Kruk Marcin, Ralston Stuart H, Albagha Omar M E
Abstract excerpt
Genetic factors are important in the pathogenesis of osteoporosis, but little is known about the genetic determinants of treatment response. Previous studies have shown that polymorphisms of the LRP5 gene are associated with bone mineral density (BMD), but the relationship between LRP5 polymorphisms and response to bisphosphonate treatment in osteoporosis has not been studied. In this study we investigated LRP5...
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