Article
MYD88 L265P mutations are correlated with 6q deletion in Korean patients with Waldenström macroglobulinemia.
BioMed research international - 1 Jan 2014
Kim Jung-Ah, Im Kyongok, Park Si Nae, Kwon Jiseok, Choi Qute, Hwang Sang Mee, Sekiguchi Naohiro, Yoon Sung-Soo, Lee Dong Soon, Kim Seon Young
Abstract excerpt
Waldenström macroglobulinemia (WM) is a malignant lymphoplasma-proliferative disorder with IgM monoclonal gammopathy. A recent whole-genome study identified MYD88 L265P as the key mutation in WM. We investigated MYD88 mutations in conjunction with cytogenetic study in 22 consecutive Korean WM patients. Conventional G-banding and interphase fluorescence in situ hybridization (FISH) were performed at regions...
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