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Article

Association between the MTHFR A1298C polymorphism and risk of cancer: evidence from 265 case-control studies.

Molecular genetics and genomics : MGG - 1 Feb 2016

Zhu Xin-Li, Liu Zhi-Zhong, Yan Sen-Xiang, Wang Wei, Chang Rui-Xia, Zhang Chun-Yan, Guo Yan

Abstract excerpt

Many molecular, epidemiological studies have been performed to explore the association between MTHFR A1298C polymorphism and cancer risk. However, the results were inconsistent or even contradictory. Hence, we performed a meta-analysis to investigate the association between cancer risk and MTHFR A1298C (81,040 cases and 114,975 controls from 265 studies) polymorphism. Overall, significant association was observed...

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Identifiers

PMID: 26156333
DOI: 10.1007/s00438-015-1082-y

Genes

MTHFR

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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