Article
Paternal RNA contributions in the Caenorhabditis elegans zygote.
The EMBO journal - 18 Aug 2014
Stoeckius Marlon, Grün Dominic, Rajewsky Nikolaus
Abstract excerpt
Development of the early embryo is thought to be mainly driven by maternal gene products and post-transcriptional gene regulation. Here, we used metabolic labeling to show that RNA can be transferred by sperm into the oocyte upon fertilization. To identify genes with paternal expression in the embryo, we performed crosses of males and females from divergent Caenorhabditis elegans strains. RNA sequencing of mRNAs...
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