Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The generation of macrophages with anti-inflammatory activity in the absence of STAT6 signaling.

Journal of leukocyte biology - 1 Sept 2015

Fleming Bryan D, Chandrasekaran Prabha, Dillon Laura A L, Dalby Elizabeth, Suresh Rahul, Sarkar Arup, El-Sayed Najib M, Mosser David M

Abstract excerpt

Macrophages readily change their phenotype in response to exogenous stimuli. In this work, macrophages were stimulated under a variety of experimental conditions, and phenotypic alterations were correlated with changes in gene expression. We identified 3 transcriptionally related populations of macrophages with immunoregulatory activity. They were generated by stimulating cells with TLR ligands in the presence of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Inflammatory Agents
Share to Chemokines

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunomodulation

Share to Interleukin-4

Share to Lactic Acid

Share to Macrophage Activation

Share to Metabolic Networks and Pathways

Share to STAT6 Transcription Factor

Source

Open in PubMed Open full text

Identifiers

PMID: 26048978
DOI: 10.1189/jlb.2A1114-560R
PMCID: PMC4541501

Genes

STAT6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The generation of macrophages with anti-inflammatory activity in the absence of STAT6 signaling.PMID 26048978Read ↗

Regulatory macrophages: setting the threshold for therapy.Semantic proximity Read ↗

Reprogram to Heal: Macrophage Phenotypes as Living TherapeuticsSemantic proximity Read ↗

Phenotypic Alteration of BMDM In Vitro Using Small Interfering RNA.Semantic proximity Read ↗

High-throughput phenotypic screen and transcriptional analysis identify new compounds and targets for macrophage reprogramming.Semantic proximity Read ↗

The transition of M-CSF-derived human macrophages to a growth-promoting phenotype.Semantic proximity Read ↗

Regulatory Macrophages Inhibit Alternative Macrophage Activation and Attenuate Pathology Associated with Fibrosis.Semantic proximity Read ↗

Macrophage-based therapeutic strategies in regenerative medicine.Semantic proximity Read ↗

Macrophage phenotypes and functions: resolving inflammation and restoring homeostasis.Semantic proximity Read ↗

Current Concept and Update of the Macrophage Plasticity Concept: Intracellular Mechanisms of Reprogramming and M3 Macrophage "Switch" Phenotype.Semantic proximity Read ↗

Non-canonical alternatives: What a macrophage is 4Semantic proximity Read ↗

Macrophages in Tissue Repair, Regeneration, and Fibrosis.Semantic proximity Read ↗

Induction of a distinct macrophage population and protection from lung injury and fibrosis by Notch2 blockadeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.