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Article

Use of next-generation sequencing to detect mutations associated with antiviral drug resistance in cytomegalovirus.

Journal of clinical microbiology - 24 Oct 2023

Streck Nicholas T, Espy Mark J, Ferber Matthew J, Klee Eric W, Razonable Raymund R, Gonzalez Dimitri, Sayada Chalom, Heaton Phillip R, Chou Sunwen, Binnicker Matthew J

Abstract excerpt

Cytomegalovirus (CMV) is a significant cause of morbidity and mortality among immunocompromised hosts, including transplant recipients. Antiviral prophylaxis or treatment is used to reduce the incidence of CMV disease in this patient population; however, there is concern about increasing antiviral resistance. Detection of antiviral resistance in CMV was traditionally accomplished using Sanger sequencing of UL54...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 37750719
DOI: 10.1128/jcm.00429-23
PMCID: PMC10595055

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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