Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Detection of antiviral drug resistance in patients with congenital cytomegalovirus infection using long-read sequencing: a retrospective observational study.

BMC infectious diseases - 22 Jun 2022

Torii Yuka, Horiba Kazuhiro, Kawada Jun-Ichi, Haruta Kazunori, Yamaguchi Makoto, Suzuki Takako, Uryu Hideko, Kashiwa Naoyuki, Goishi Keiji, Ogi Tomoo, Ito Yoshinori

Abstract excerpt

BACKGROUND: Congenital human cytomegalovirus (cCMV) infection can cause sensorineural hearing loss and neurodevelopmental disabilities in children. Ganciclovir and valganciclovir (GCV/VGCV) improve long-term audiologic and neurodevelopmental outcomes for patients with cCMV infection; however, antiviral drug resistance has been documented in some cases. Long-read sequencing can be used for the detection of drug...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antiviral Agents
Share to Child

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytomegalovirus Infections

Share to Drug Resistance, Viral

Share to Ganciclovir

Share to Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 35733089
DOI: 10.1186/s12879-022-07537-6
PMCID: PMC9219161

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Detection of antiviral drug resistance in patients with congenital cytomegalovirus infection using long-read sequencing: a retrospective observational study.PMID 35733089Read ↗

Use of next-generation sequencing to detect mutations associated with antiviral drug resistance in cytomegalovirus.Semantic proximity Read ↗

Long-range PCRs and next-generation sequencing to detect cytomegalovirus drug resistance-associated mutations.Semantic proximity Read ↗

Human Cytomegalovirus (HCMV) Genetic Diversity, Drug Resistance Testing and Prevalence of the Resistance Mutations: A Literature ReviewSemantic proximity Read ↗

Next-generation sequencing for cytomegalovirus genotypic antiviral resistance testing.Semantic proximity Read ↗

Cytomegalovirus antiviral resistance: characterization of results from clinical specimens.Semantic proximity Read ↗

Next-generation sequencing for cytomegalovirus antiviral resistance genotyping in a clinical virology laboratory.Semantic proximity Read ↗

Improved detection of emerging drug-resistant mutant cytomegalovirus subpopulations by deep sequencing.Semantic proximity Read ↗

Drug-resistant cytomegalovirus: clinical implications of specific mutations.Semantic proximity Read ↗

Advances in the genotypic diagnosis of cytomegalovirus antiviral drug resistance.Semantic proximity Read ↗

Rapid detection of human cytomegalovirus UL97 and UL54 mutations directly from patient samples.Semantic proximity Read ↗

Detection of Low Frequency Multi-Drug Resistance and Novel Putative Maribavir Resistance in Immunocompromised Pediatric Patients with CytomegalovirusSemantic proximity Read ↗

Onset of valganciclovir resistance in two infants with congenital cytomegalovirus infection.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.