Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Rapid detection of human cytomegalovirus UL97 and UL54 mutations directly from patient samples.

Journal of clinical microbiology - 1 Jul 2013

Hall Sedlak Ruth, Castor Jared, Butler-Wu Susan M, Chan Elaine, Cook Linda, Limaye Ajit P, Jerome Keith R

Abstract excerpt

Human cytomegalovirus (CMV) is a significant contributor to morbidity and mortality in immunocompromised patients, particularly in the transplant setting. The availability of anti-CMV drugs has improved treatment, but drug resistance is an emerging problem. Here, we describe an improved, rapid, sequencing-based assay for the two genes in CMV where drug resistance occurs, the UL97 and UL54 genes. This assay is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytomegalovirus
Share to Cytomegalovirus Infections

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA-Directed DNA Polymerase

Share to Drug Resistance, Viral

Share to Molecular Diagnostic Techniques

Share to Mutant Proteins

Share to Phosphotransferases (Alcohol Group Acceptor)

Share to Virology

Source

Open in PubMed Open full text

Identifiers

PMID: 23678068
DOI: 10.1128/JCM.00611-13
PMCID: PMC3697653

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Rapid detection of human cytomegalovirus UL97 and UL54 mutations directly from patient samples.PMID 23678068Read ↗

Use of next-generation sequencing to detect mutations associated with antiviral drug resistance in cytomegalovirus.Semantic proximity Read ↗

Detection of Cytomegalovirus Drug Resistance Mutations by Next-Generation SequencingSemantic proximity Read ↗

Cytomegalovirus antiviral resistance: characterization of results from clinical specimens.Semantic proximity Read ↗

Rapid Detection Directly from Patient Serum Samples of Human Cytomegalovirus UL97 Mutations Conferring Ganciclovir ResistanceSemantic proximity Read ↗

Long-range PCRs and next-generation sequencing to detect cytomegalovirus drug resistance-associated mutations.Semantic proximity Read ↗

Clinical next-generation sequencing assay combining full-length gene amplification and shotgun sequencing for the detection of CMV drug resistance mutations.Semantic proximity Read ↗

The genetic basis of human cytomegalovirus resistance and current trends in antiviral resistance analysis.Semantic proximity Read ↗

Sequencing of cytomegalovirus UL97 gene for genotypic antiviral resistance testing.Semantic proximity Read ↗

Drug-resistant cytomegalovirus in transplant recipients: a French cohort study.Semantic proximity Read ↗

Development and validation of a next-generation sequencing assay with open-access analysis software for detecting resistance-associated mutations in CMV.Semantic proximity Read ↗

Improved detection of emerging drug-resistant mutant cytomegalovirus subpopulations by deep sequencing.Semantic proximity Read ↗

Molecular Epidemiology of Cytomegalovirus UL97 and UL54 variants in Taiwan.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.