Article
Mutational status of KRAS, NRAS, and BRAF in primary clear cell ovarian carcinoma.
Virchows Archiv : an international journal of pathology - 1 Aug 2014
Zannoni Gian Franco, Improta Giuseppina, Chiarello Gaia, Pettinato Angela, Petrillo Marco, Scollo Paolo, Scambia Giovanni, Fraggetta Filippo
Abstract excerpt
Ovarian clear cell carcinoma (OCCC) is a subtype of epithelial ovarian cancer with characteristic biological features and aggressive clinical behavior. OCCCs show a pattern of gene mutations different from other type I ovarian malignancies, notably a higher frequency of PIK3CA mutations. In low g...
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