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Article

High frequency of BRAF mutations and concomitant KRAS mutations in Taiwanese ovarian clear cell carcinoma.

Taiwanese journal of obstetrics & gynecology - 1 Mar 2026

Shen Huang-Pin, Lee Ming-Yung, Chao Wan-Ru, Lee Yi-Ju, Sheu Gwo-Tarng, Wang Pi-Chieh, Chen Chi-Kuan, Han Chih-Ping

Abstract excerpt

OBJECTIVES: Given encouraging clinical evidence of BRAF inhibitors for melanoma, etc., we investigated BRAF mutation status in ovarian clear cell carcinoma (OCCC) from Taiwanese women and assessed the association of BRAF mutation with KRAS mutation. MATERIALS AND METHODS: DNA was extracted from microdissected tissue samples and analyzed for BRAF mutations in exon 15, around the activation segment (AS), using a...

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Identifiers

PMID: 41813377
DOI: 10.1016/j.tjog.2024.12.036

Genes

BRAF
KRAS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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