Article
Clinicopathological correlates and prognostic significance of KRAS mutation status in a pooled prospective cohort of epithelial ovarian cancer.
Diagnostic pathology - 25 Jun 2013
Nodin Björn, Zendehrokh Nooreldin, Sundström Magnus, Jirström Karin
Abstract excerpt
BACKGROUND: Activating KRAS mutations are common in ovarian carcinomas of low histological grade, less advanced clinical stage and mucinous histological subtype, and form part of the distinct molecular alterations associated with type I tumors in the dualistic model of ovarian carcinogenesis. Here, we investigated the occurrence, clinicopathological correlates and prognostic significance of specific KRAS...
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