Article
Frequent activating mutations of PIK3CA in ovarian clear cell carcinoma.
The American journal of pathology - 1 May 2009
Kuo Kuan-Ting, Mao Tsui-Lien, Jones Siân, Veras Emanuela, Ayhan Ayse, Wang Tian-Li, Glas Ruth, Slamon Dennis, Velculescu Victor E, Kuman Robert J, Shih Ie-Ming
Abstract excerpt
Ovarian clear cell carcinoma (CCC) is one of the most malignant types of ovarian carcinomas, particularly at advanced stages. Unlike the more common type of ovarian cancer, high-grade serous carcinoma, ovarian CCC is often resistant to platinum-based chemotherapy, and therefore an effective treat...
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