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Article

CCNE1 copy-number gain and overexpression identify ovarian clear cell carcinoma with a poor prognosis.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Feb 2017

Ayhan Ayse, Kuhn Elisabetta, Wu Ren-Chin, Ogawa Hiroshi, Bahadirli-Talbott Asli, Mao Tsui-Lien, Sugimura Haruhiko, Shih Ie-Ming, Wang Tian-Li

Abstract excerpt

Ovarian clear cell carcinoma is a unique type of ovarian cancer, often derived from endometriosis, and advanced-stage disease has a dismal prognosis primarily due to the resistance to conventional chemotherapy. Previous studies have shown frequent somatic mutations in ARID1A, PIK3CA, hTERT promoter, and amplification of ZNF217; however, the molecular alterations that are associated with its aggressiveness remain...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27767100
DOI: 10.1038/modpathol.2016.160

Genes

CCNE1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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