Article
Contribution of genetic variation to transgenerational inheritance of DNA methylation.
Genome biology - 29 May 2014
McRae Allan F, Powell Joseph E, Henders Anjali K, Bowdler Lisa, Hemani Gibran, Shah Sonia, Painter Jodie N, Martin Nicholas G, Visscher Peter M, Montgomery Grant W
Abstract excerpt
BACKGROUND: Despite the important role DNA methylation plays in transcriptional regulation, the transgenerational inheritance of DNA methylation is not well understood. The genetic heritability of DNA methylation has been estimated using twin pairs, although concern has been expressed whether the...
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