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Article

Extensive variation and low heritability of DNA methylation identified in a twin study.

Genome research - 1 Nov 2011

Gervin Kristina, Hammerø Martin, Akselsen Hanne E, Moe Rune, Nygård Heidi, Brandt Ingunn, Gjessing Håkon K, Harris Jennifer R, Undlien Dag E, Lyle Robert

Abstract excerpt

Disturbance of DNA methylation leading to aberrant gene expression has been implicated in the etiology of many diseases. Whereas variation at the genetic level has been studied extensively, less is known about the extent and function of epigenetic variation. To explore variation and heritability of DNA methylation, we performed bisulfite sequencing of 1760 CpG sites in 186 regions in the human major...

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Identifiers

PMID: 21948560
DOI: 10.1101/gr.119685.110
PMCID: PMC3205566

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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