Article
Liver X receptors alpha gene (NR1H3) promoter polymorphisms are associated with systemic lupus erythematosus in Koreans.
Arthritis research & therapy - 14 May 2014
Jeon Ja-Young, Nam Jin-Young, Kim Hyoun-Ah, Park Yong-Beom, Bae Sang-Cheol, Suh Chang-Hee
Abstract excerpt
INTRODUCTION: Liver X receptors are established sensors of lipid and cholesterol homeostasis. Recent studies have reported that these receptors are involved in the regulation of inflammation and immune responses. We attempted to identify single nucleotide polymorphisms (SNPs) of the NR1H3 gene associated with the susceptibility to systemic lupus erythematosus (SLE). METHODS: SNPs were genotyped using SNaPSHOT...
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