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Article

Association between polymorphisms of the IKZF3 gene and systemic lupus erythematosus in a Chinese Han population.

PloS one - 1 Jan 2014

Cai Xinze, Qiao Ying, Diao Cheng, Xu Xiaoxue, Chen Yang, Du Shuyan, Liu Xudong, Liu Nan, Yu Shuang, Chen Dong, Jiang Yi

Abstract excerpt

OBJECTIVE: It has been reported that IKAROS family of zinc finger 3 (IKZF3)-deficient mice spontaneously develop human systemic lupus erythematosus (SLE)-like phenotypes and produce anti-dsDNA Ab leading to immune complex-mediated glomerulonephritis. Polymorphism of the IKZF3 gene corresponds with the susceptibility to several immune-related diseases. Our intention was to establish an association between...

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Source

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Identifiers

PMID: 25271777
DOI: 10.1371/journal.pone.0108661
PMCID: PMC4182708

Genes

IKZF3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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