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Article

A common polymorphism in NR1H2 (LXRbeta) is associated with preeclampsia.

BMC medical genetics - 26 Oct 2011

Mouzat Kevin, Mercier Eric, Polge Anne, Evrard Alexandre, Baron Silvère, Balducchi Jean-Pierre, Brouillet Jean-Paul, Lumbroso Serge, Gris Jean-Christophe

Abstract excerpt

BACKGROUND: Preeclampsia is a frequent complication of pregnancy and a leading cause of perinatal mortality. Both genetic and environmental risk factors have been identified. Lipid metabolism, particularly cholesterol metabolism, is associated with this disease. Liver X receptors alpha (NR1H3, also known as LXRalpha) and beta (NR1H2, also known as LXRbeta) play a key role in lipid metabolism. They belong to the...

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Identifiers

PMID: 22029530
DOI: 10.1186/1471-2350-12-145
PMCID: PMC3214159

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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