Article
Nuclear receptor variants in liver disease.
Digestive diseases (Basel, Switzerland) - 1 Jan 2015
Zimmer Vincent, Liebe Roman, Lammert Frank
Abstract excerpt
This snapshot reviews the current state of knowledge on genetic variants of nuclear receptors (NRs) involved in regulating various aspects of liver metabolism. Interindividual differences in responses to diet and other 'in-' and environmental stressors can be caused by variants in components of the NR regulatory gene network. We recapitulate recent evidence for the application of NRs in genetic diagnosis of...
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