Article
Combining calls from multiple somatic mutation-callers.
BMC bioinformatics - 21 May 2014
Kim Su Yeon, Jacob Laurent, Speed Terence P
Abstract excerpt
BACKGROUND: Accurate somatic mutation-calling is essential for insightful mutation analyses in cancer studies. Several mutation-callers are publicly available and more are likely to appear. Nonetheless, mutation-calling is still challenging and there is unlikely to be one established caller that systematically outperforms all others. Therefore, fully utilizing multiple callers can be a powerful way to construct a...
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