Article
Simple combination of multiple somatic variant callers to increase accuracy.
Scientific reports - 25 May 2023
Trevarton Alexander J, Chang Jeffrey T, Symmans W Fraser
Abstract excerpt
Publications comparing variant caller algorithms present discordant results with contradictory rankings. Caller performances are inconsistent and wide ranging, and dependent upon input data, application, parameter settings, and evaluation metric. With no single variant caller emerging as a superior standard, combinations or ensembles of variant callers have appeared in the literature. In this study, a whole...
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