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Article

The NQO1 Pro187Ser polymorphism and breast cancer susceptibility: evidence from an updated meta-analysis.

Diagnostic pathology - 29 May 2014

Peng Qiliu, Lu Yu, Lao Xianjun, Chen Zhiping, Li Ruolin, Sui Jingzhe, Qin Xue, Li Shan

Abstract excerpt

BACKGROUND NAD(P)H: quinone oxidoreductase 1 (NQO1) plays a central role in catalyzing the two-electron reduction of quinoid compounds into hydroquinones. The NQO1 Pro187Ser polymorphism was found to correlate with a lower enzymatic activity, which may result in increased incidence of carcinomas including breast cancer. Previous studies investigating the association between NQO1 Pro187Ser polymorphism and breast...

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Source

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Identifiers

PMID: 24884893
DOI: 10.1186/1746-1596-9-100
PMCID: PMC4041044

Genes

NQO1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The NQO1 Pro187Ser polymorphism and breast cancer susceptibility: evidence from an updated meta-analysis.PMID 24884893Read ↗

Evidence on the association between NQO1 Pro187Ser polymorphism and breast cancer risk in the current studies: a meta-analysis.Semantic proximity Read ↗

Association between NQO1 Pro187Ser polymorphism and esophageal cancer: a meta-analysis.Semantic proximity Read ↗

The association between NQO1 Pro187Ser polymorphism and bladder cancer susceptibility: a meta-analysis of 15 studies.Semantic proximity Read ↗

The association between NQO1 Pro187Ser polymorphism and urinary system cancer susceptibility: a meta-analysis of 22 studies.Semantic proximity Read ↗

Meta-analysis of the association between NQO1 Pro187Ser polymorphism and colorectal cancer in Asians.Semantic proximity Read ↗

The C609T (Pro187Ser) Null Polymorphism of the NQO1 Gene Contributes Significantly to Breast Cancer Susceptibility in North Indian Populations: a Case Control Study.Semantic proximity Read ↗

NAD(P)H:quinone oxidoreductase 1 (NQO1) Pro187Ser polymorphism and the risk of lung, bladder, and colorectal cancers: a meta-analysis.Semantic proximity Read ↗

Association of NQO1 Pro187Ser polymorphism with the risks for colorectal cancer and colorectal adenoma: a meta-analysis.Semantic proximity Read ↗

Contribution of NAD(P)H quinone oxidoreductase 1 (NQO1) Pro187Ser polymorphism and risk of colorectal adenoma and colorectal cancer in Caucasians: a meta-analysis.Semantic proximity Read ↗

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NAD(P)H:quinone oxidoreductase 1 Pro187Ser polymorphism and expression do not cosegregate with clinico-pathological characteristics of human mammary tumors.Semantic proximity Read ↗

NAD(P)H:quinone oxidoreductase 1 Arg139Trp and Pro187Ser polymorphisms imbalance estrogen metabolism towards DNA adduct formation in human mammary epithelial cells.Semantic proximity Read ↗

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