Article
Association of NQO1 polymorphism with spontaneous breast cancer in two independent populations.
British journal of cancer - 17 May 2004
Menzel H-J, Sarmanova J, Soucek P, Berberich R, Grünewald K, Haun M, Kraft H-G
Abstract excerpt
Eight different single-nucleotide polymorphisms (SNPs) in six different genes were investigated for possible association with breast cancer. We used a case-control study design in two Caucasian populations, one from Tyrol, Austria, and the other from Prague, Czech Republic. Two SNPs showed an association with breast cancer: R72P inTP53 and P187S in NQO1. Six SNPs, Q356R and P871L in BRCA1, N372H in BRCA2, C112R...
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