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Article

Association of NQO1 polymorphism with spontaneous breast cancer in two independent populations.

British journal of cancer - 17 May 2004

Menzel H-J, Sarmanova J, Soucek P, Berberich R, Grünewald K, Haun M, Kraft H-G

Abstract excerpt

Eight different single-nucleotide polymorphisms (SNPs) in six different genes were investigated for possible association with breast cancer. We used a case-control study design in two Caucasian populations, one from Tyrol, Austria, and the other from Prague, Czech Republic. Two SNPs showed an association with breast cancer: R72P inTP53 and P187S in NQO1. Six SNPs, Q356R and P871L in BRCA1, N372H in BRCA2, C112R...

Topics

Adult
Aged
Aged, 80 and over
Breast Neoplasms
Case-Control Studies
Female
Genetic Predisposition to Disease
Heterozygote
Humans
Middle Aged
NAD(P)H Dehydrogenase (Quinone)

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Odds Ratio

Polymorphism, Single Nucleotide

Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 15138483
DOI: 10.1038/sj.bjc.6601779
PMCID: PMC2410282

Genes

NQO1
BRCA1
BRCA2
GNB3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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Association of NQO1 polymorphism with spontaneous breast cancer in two independent populations.PMID 15138483Read ↗

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