Article
Association of genetic polymorphisms with histological grading of necroinflammation, staging of fibrosis, and liver function in Mexicans with chronic hepatitis C virus infection.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research - 1 Oct 2013
Sánchez-Parada María Guadalupe, Alvarez-Rodríguez Bertha Adriana, Gómez-Meda Belinda Claudia, Troyo-Sanromán Rogelio, Sánchez-Orozco Laura Verónica, Zamora-Perez Ana Lourdes, Landeros Martha Silvia Lucano, Armendáriz-Borunda Juan
Abstract excerpt
BACKGROUND/AIM: The aim of this work was to establish an association between the single-nucleotide polymorphisms (SNPs) of TGFB1 (rs1800471), AT (rs3789679), MMP-1 (rs17886084), MMP-3 (rs35068180), and PAI-1 (rs1799889) and the histological grading of necroinflammation, staging of hepatic fibrosis, and liver function in Mexican patients with advanced liver fibrosis due to chronic hepatitis C virus infection....