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Article

Decision-making during NHEJ: a network of interactions in human Polμ implicated in substrate recognition and end-bridging.

Nucleic acids research - 1 Jul 2014

Martin Maria Jose, Blanco Luis

Abstract excerpt

Human Polμ is a DNA polymerase belonging to the X family that has been implicated in the non-homologous end-joining (NHEJ) pathway during repair of double-strand breaks in DNA. Loop1 is a flexible piece of Polμ which has a critical role during terminal transferase and end-joining activities: it acts as a pseudo-template when the template strand is discontinuous or unavailable, whilst diffusing away if present to...

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Identifiers

PMID: 24878922
DOI: 10.1093/nar/gku475
PMCID: PMC4081086

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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