Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Structures of PI4KIIIβ complexes show simultaneous recruitment of Rab11 and its effectors.

Science (New York, N.Y.) - 30 May 2014

Burke John E, Inglis Alison J, Perisic Olga, Masson Glenn R, McLaughlin Stephen H, Rutaganira Florentine, Shokat Kevan M, Williams Roger L

Abstract excerpt

Phosphatidylinositol 4-kinases (PI4Ks) and small guanosine triphosphatases (GTPases) are essential for processes that require expansion and remodeling of phosphatidylinositol 4-phosphate (PI4P)-containing membranes, including cytokinesis, intracellular development of malarial pathogens, and repli...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antimalarials
Share to Crystallography, X-Ray
Share to Drug Design

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to I-kappa B Kinase

Share to Phosphotransferases (Alcohol Group Acceptor)

Share to Plasmodium

Share to Protein Structure, Secondary

Share to rab GTP-Binding Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 24876499
DOI: 10.1126/science.1253397
PMCID: PMC4046302

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24876499-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Structures of PI4KIIIβ complexes show simultaneous recruitment of Rab11 and its effectors.PMID 24876499Read ↗

Crystal structure of rab11 in complex with rab11 family interacting protein 2.Semantic proximity Read ↗

Cryo‐EM structure of metazoan TRAPPIII, the multi‐subunit complex that activates the GTPase Rab1Semantic proximity Read ↗

Structural basis for Rab11-mediated recruitment of FIP3 to recycling endosomes.Semantic proximity Read ↗

Structural insights into assembly and regulation of the plasma membrane phosphatidylinositol 4-kinase complex.Semantic proximity Read ↗

Biophysical and Structural Characterization of Novel RAS-Binding Domains (RBDs) of PI3Kα and PI3Kγ.Semantic proximity Read ↗

Peptides targeting RAB11A–FIP2 complex inhibit HPIV3, RSV, and IAV replication as broad-spectrum antiviralsSemantic proximity Read ↗

Structure of the phosphoinositide 3-kinase p110γ-p101 complex reveals molecular mechanism of GPCR activationSemantic proximity Read ↗

Solution structure of the phosphatidylinositol 3-phosphate binding domain from the <i>Legionella</i> effector SetASemantic proximity Read ↗

Structural determinants of Rab11 activation by the guanine nucleotide exchange factor SH3BP5.Semantic proximity Read ↗

A cryo-EM structure of metazoan TRAPPIII, the multisubunit complex that activates the GTPase Rab1Semantic proximity Read ↗

Crystal structure of IIGP1: a paradigm for interferon-inducible p47 resistance GTPases.Semantic proximity Read ↗

The ARF GTPases: defining roles in membrane traffic and organelle structure.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.