Article
Crystal structure of rab11 in complex with rab11 family interacting protein 2.
Structure (London, England : 1993) - 1 Aug 2006
Jagoe William N, Lindsay Andrew J, Read Randy J, McCoy Airlie J, McCaffrey Mary W, Khan Amir R
Abstract excerpt
The small GTPase Rab11 regulates the recycling of endosomes to the plasma membrane via interactions with the Rab11 family of interacting proteins (FIPs). FIPs contain a highly conserved Rab binding domain (RBD) at their C termini whose structure is unknown. Here, we have determined the crystal structure of the RBD of FIP2 in complex with Rab11(GTP) by single wavelength anomalous diffraction methods. The overall...
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