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Article

Structural basis for Rab11-mediated recruitment of FIP3 to recycling endosomes.

Journal of molecular biology - 24 Nov 2006

Eathiraj Sudharshan, Mishra Ashwini, Prekeris Rytis, Lambright David G

Abstract excerpt

The Rab11 GTPase regulates recycling of internalized plasma membrane receptors and is essential for completion of cytokinesis. A family of Rab11 interacting proteins (FIPs) that conserve a C-terminal Rab-binding domain (RBD) selectively recognize the active form of Rab11. Normal completion of cytokinesis requires a complex between Rab11 and FIP3. Here, we report the crystal structure and mutational analysis of a...

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Identifiers

PMID: 17007872
DOI: 10.1016/j.jmb.2006.08.064

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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