Excessive fuel availability amplifies the FTO-mediated obesity risk: results from the TUEF and Whitehall II studies.

doi:10.1038/s41598-017-15744-4

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Article

Excessive fuel availability amplifies the FTO-mediated obesity risk: results from the TUEF and Whitehall II studies.

Scientific reports - 14 Nov 2017

Wagner Róbert, Tabák Ádám G, Fehlert Ellen, Fritsche Louise, Jaghutriz Benjamin A, Bánhegyi Róbert J, Schmid Sebastian M, Staiger Harald, Machicao Fausto, Peter Andreas, Häring Hans-Ulrich, Fritsche Andreas, Heni Martin

Abstract excerpt

Variation in FTO is the most important common genetic determinant of body weight. Altered energy metabolism could underlie this association. We hypothesized that higher circulating glucose or triglycerides can amplify the FTO impact on BMI. In 2671 subjects of the TUEF study, we investigated the interaction effect of fasting glucose and triglyceride levels with rs9939609 in FTO on BMI. We analysed the same...

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PMID: 29138452
DOI: 10.1038/s41598-017-15744-4
PMCID: PMC5686126

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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