Dietary Intake, FTO Genetic Variants, and Adiposity: A Combined Analysis of Over 16,000 Children and Adolescents.

doi:10.2337/db14-1629

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Dietary Intake, FTO Genetic Variants, and Adiposity: A Combined Analysis of Over 16,000 Children and Adolescents.

Diabetes - 1 Jul 2015

Qi Qibin, Downer Mary K, Kilpeläinen Tuomas O, Taal H Rob, Barton Sheila J, Ntalla Ioanna, Standl Marie, Boraska Vesna, Huikari Ville, Kiefte-de Jong Jessica C, Körner Antje, Lakka Timo A, Liu Gaifen, Magnusson Jessica, Okuda Masayuki, Raitakari Olli, Richmond Rebecca, Scott Robert A, Bailey Mark E S, Scheuermann Kathrin, Holloway John W, Inskip Hazel, Isasi Carmen R, Mossavar-Rahmani Yasmin, Jaddoe Vincent W V, Laitinen Jaana, Lindi Virpi, Melén Erik, Pitsiladis Yannis, Pitkänen Niina, Snieder Harold, Heinrich Joachim, Timpson Nicholas J, Wang Tao, Yuji Hinoda, Zeggini Eleftheria, Dedoussis George V, Kaplan Robert C, Wylie-Rosett Judith, Loos Ruth J F, Hu Frank B, Qi Lu

Abstract excerpt

The FTO gene harbors variation with the strongest effect on adiposity and obesity risk. Previous data support a role for FTO variation in influencing food intake. We conducted a combined analysis of 16,094 boys and girls aged 1-18 years from 14 studies to examine the following: 1) the association between the FTO rs9939609 variant (or a proxy) and total energy and macronutrient intake; and 2) the interaction...

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Adiposity
Alpha-Ketoglutarate-Dependent Dioxygenase FTO

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Body Mass Index

Cross-Sectional Studies

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PMID: 25720386
DOI: 10.2337/db14-1629
PMCID: PMC4876751

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