Article
FTO affects food cravings and interacts with age to influence age-related decline in food cravings.
Physiology & behavior - 1 Aug 2018
Dang Linh C, Samanez-Larkin Gregory R, Smith Christopher T, Castrellon Jaime J, Perkins Scott F, Cowan Ronald L, Claassen Daniel O, Zald David H
Abstract excerpt
The fat mass and obesity associated gene (FTO) was the first gene identified by genome-wide association studies to correlate with higher body mass index (BMI) and increased odds of obesity. FTO remains the locus with the largest and most replicated effect on body weight, but the mechanism whereby FTO affects body weight and the development of obesity is not fully understood. Here we tested whether FTO is...
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