Nucleotide‐binding oligomerization domain 1 regulates <i>Porphyromonas gingivalis</i>‐induced vascular cell adhesion molecule 1 and intercellular adhesion molecule 1 expression in endothelial cells through <scp>NF</scp>‐κB pathway

Abstract excerpt

BACKGROUND AND OBJECTIVE: Porphyromonas gingivalis has been shown to actively invade endothelial cells and induce vascular cell adhesion molecule 1 (VCAM-1) and intercellular adhesion molecule 1 (ICAM-1) overexpression. Nucleotide-binding oligomerization domain 1 (NOD1) is an intracellular pattern recognition reporter, and its involvement in this process was unknown. This study focused on endothelial cells...

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