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<i>Porphyromonas gingivalis</i>Fimbria-Dependent Activation of Inflammatory Genes in Human Aortic Endothelial Cells

19 Aug 2005

Abstract excerpt

Epidemiological and pathological studies have suggested that infection with the oral pathogen Porphyromonas gingivalis can potentiate atherosclerosis and human coronary heart disease. Furthermore, infection with invasive, but not noninvasive P. gingivalis has been demonstrated to accelerate atherosclerosis in apolipoprotein E-deficient (ApoE(-/-)) mice and to accelerate local inflammatory responses in aortic...

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PMID: 16113252
DOI: 10.1128/iai.73.9.5367-5378.2005

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