Article
Nucleotide-binding oligomerization domain proteins are innate immune receptors for internalized Streptococcus pneumoniae.
The Journal of biological chemistry - 27 Aug 2004
Opitz Bastian, Püschel Anja, Schmeck Bernd, Hocke Andreas C, Rosseau Simone, Hammerschmidt Sven, Schumann Ralf R, Suttorp Norbert, Hippenstiel Stefan
Abstract excerpt
Streptococcus pneumoniae, the major cause of community-acquired pneumonia and bacterial meningitis, has been shown to transiently invade epithelial and endothelial cells. Innate immune receptors including Toll-like receptors recognize various pathogens, such as S. pneumoniae, by identifying conse...
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