Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Impact of tumor necrosis factor receptor p55 deficiency in susceptibility of C57BL/6 mice to infection with Leishmania (Leishmania) amazonensis.

Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi - 1 Apr 2016

Cargnelutti Diego Esteban, Salomón María Cristina, Celedon Verónica, Cuello-Carrión Fernando Darío, Gea Susana, Di Genaro María Silvia, Scodeller Eduardo Alberto

Abstract excerpt

Tumor necrosis factor (TNF) is involved in host resistance to several intracellular pathogens. Although the critical role of TNF receptor (TNFR)p55 in Leishmania (Leishmania) major infection has been demonstrated, the impact of TNFRp55 deficiency on L. (L.) amazonensis infection has not been explored. L. (L.) amazonensis-infected TNFRp55(-/-) mice failed to resolve lesions, whereas C57BL/6 wild-type mice...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to TNF gene
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leishmaniasis, Cutaneous

Share to Mice, Inbred C57BL

Share to Mice, Knockout

Share to Receptors, Tumor Necrosis Factor, Type I

Source

Identifiers

PMID: 24856420
DOI: 10.1016/j.jmii.2014.03.009

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Impact of tumor necrosis factor receptor p55 deficiency in susceptibility of C57BL/6 mice to infection with Leishmania (Leishmania) amazonensis.PMID 24856420Read ↗

Loss of TNF signaling facilitates the development of a novel Ly-6C(low) macrophage population permissive for Leishmania major infection.Semantic proximity Read ↗

Rapidly fatal leishmaniasis in resistant C57BL/6 mice lacking TNF.Semantic proximity Read ↗

The resistance against Listeria monocytogenes and the formation of germinal centers depend on a functional death domain of the 55 kDa tumor necrosis factor receptor.Semantic proximity Read ↗

Infection of C57BL/10ScCr and C57BL/10ScNCr mice withLeishmania majorreveals a role for Toll-like receptor 4 in the control of parasite replicationSemantic proximity Read ↗

Phenotypic analysis of TNFR1-deficient mice and characterization of TNFR1-deficient fibroblasts in vitro.Semantic proximity Read ↗

Tumor necrosis factor receptor 2 plays a minor role for mycobacterial immunity.Semantic proximity Read ↗

Susceptibility to Intracellular Infections: Contributions of TNF to Immune DefenseSemantic proximity Read ↗

microRNA-721 is a host regulator of TNF-IRF1 axis in <i>Leishmania</i> infected macrophageSemantic proximity Read ↗

Up-regulation of T helper 2 and down-regulation of T helper 1 cytokines during murine retrovirus-induced immunodeficiency syndrome enhances susceptibility of a resistant mouse strain to Leishmania amazonensis.Semantic proximity Read ↗

Novel tumor necrosis factor-knockout mice that lack Peyer's patches.Semantic proximity Read ↗

Mice lacking the tumour necrosis factor receptor 1 are resistant to TNF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes.Semantic proximity Read ↗

Lethal granuloma disintegration in mycobacteria-infected TNFRp55-/- mice is dependent on T cells and IL-12.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.