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Article

Analysis of ADAM17 polymorphisms and susceptibility to sporadic abdominal aortic aneurysm.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology - 1 Jan 2014

Li You, Yang Cheng, Ma Guoda, Cui Lili, Gu Xuefeng, Chen Yanyan, Zhao Bin, Wang Haiyang, Li Keshen

Abstract excerpt

BACKGROUND: Accumulating evidence suggests that the principal TNF-α converting enzyme, a disintegrin and metalloproteinase 17 (ADAM17), is involved in the development of human abdominal aortic aneurysm (AAA). However, the association between ADAM17 gene polymorphisms and AAA has not been explored. The present study was aimed to determine the association between ADAM17 promoter polymorphisms and AAA. METHODS: A...

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Source

Identifiers

PMID: 24853957
DOI: 10.1159/000358708

Genes

ADAM17
TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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