Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Regulatory variation in HIV-1 dependency factor ZNRD1 associates with host resistance to HIV-1 acquisition.

The Journal of infectious diseases - 15 Nov 2014

An Ping, Goedert James J, Donfield Sharyne, Buchbinder Susan, Kirk Gregory D, Detels Roger, Winkler Cheryl A

Abstract excerpt

BACKGROUND: ZNRD1 was identified as a host protein required for the completion of the human immunodeficiency virus (HIV) lifecycle in a genome-wide screen using small interfering RNA gene silencing. Subsequently, a genome-wide association study (GWAS) of host determinants for HIV-1 disease identified an association of single nucleotide polymorphisms (SNPs) in the ZNRD1 region with CD4(+) T-cell depletion....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cohort Studies
Share to Disease Resistance

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA-Binding Proteins

Share to Longitudinal Studies

Share to Polymorphism, Single Nucleotide

Share to United States

Source

Open in PubMed Open full text

Identifiers

PMID: 24842830
DOI: 10.1093/infdis/jiu291
PMCID: PMC4215072

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Regulatory variation in HIV-1 dependency factor ZNRD1 associates with host resistance to HIV-1 acquisition.PMID 24842830Read ↗

ZNRD1 (zinc ribbon domain-containing 1) is a host cellular factor that influences HIV-1 replication and disease progression.Semantic proximity Read ↗

Variants in ZNRD1 gene predict HIV-1/AIDS disease progression in a Han Chinese population in Taiwan.Semantic proximity Read ↗

HIV-1 disease-influencing effects associated with ZNRD1, HCP5 and HLA-C alleles are attributable mainly to either HLA-A10 or HLA-B*57 alleles.Semantic proximity Read ↗

Genome-wide association studies on HIV susceptibility, pathogenesis and pharmacogenomics.Semantic proximity Read ↗

Genetic associations of variants in genes encoding HIV-dependency factors required for HIV-1 infection.Semantic proximity Read ↗

Mechanisms of Immune Evasion in HIV-1: The Role of Virus-Host Protein InteractionsSemantic proximity Read ↗

Expression quantitative trait loci in long non-coding RNA ZNRD1-AS1 influence both HBV infection and hepatocellular carcinoma development.Semantic proximity Read ↗

Interdependent Dynamics of mRNA Expression and HIV-1 Viral Load: Insights from Transcriptomics and Mendelian RandomizationSemantic proximity Read ↗

A Quantitative Genetic Interaction Map of HIV Infection.Semantic proximity Read ↗

Multiancestry Genome-Wide Association Study Identifies Variants in a Zinc Finger Gene Cluster as Novel Regulators of HIV Control.Semantic proximity Read ↗

Novel genetic locus implicated for HIV-1 acquisition with putative regulatory links to HIV replication and infectivity: a genome-wide association study.Semantic proximity Read ↗

Association of SNPs in HLA-C and ZNRD1 Genes With HIV-1 Mother-to-Child Transmission in Zambia Population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.