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Article

Genome-wide association studies on HIV susceptibility, pathogenesis and pharmacogenomics.

Retrovirology - 24 Aug 2012

van Manen Daniëlle, van 't Wout Angélique B, Schuitemaker Hanneke

Abstract excerpt

Susceptibility to HIV-1 and the clinical course after infection show a substantial heterogeneity between individuals. Part of this variability can be attributed to host genetic variation. Initial candidate gene studies have revealed interesting host factors that influence HIV infection, replication and pathogenesis. Recently, genome-wide association studies (GWAS) were utilized for unbiased searches at a...

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Identifiers

PMID: 22920050
DOI: 10.1186/1742-4690-9-70
PMCID: PMC3468375

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